Micro scale electro hydrodynamic (EHD) modular cartridge pump

Current scaffold designs and materials do not provide all of the appropriate cues necessary to mimic in-vivo conditions for tissue engineering and stem cell engineering applications. It has been hypothesized that many biomaterials, such as bone, muscle, brain and heart tissue exhibit piezoelectric and ferroelectric properties. Typical cell seeding environments incorporate biochemical cues and more recently mechanical stimuli, however, electrical cues have just recently been incorporated in standard in-vitro examinations. In order to develop their potential further, novel scaffolds are required to provide adequate cues in the in-vitro environment to direct stem cells to differentiate down controlled pathways or develop novel tissue constructs. This invention is for a scaffold that provides for such cues by mimicking the native biological environment, including biochemical, topographical, mechanical and electrical cues.

This water filtration innovation is an acoustically driven molecular sieve embedded with small-diameter carbon nanotubes. First, water enters the device and contacts the filter matrix, which can be made of polymer, ceramic, or metallic compounds. Carbon nanotubes within the matrix allow only water molecules to pass through, leaving behind any larger molecules and contaminants. The unique aspect of the technology is its use of acoustics to help drive water through the filter. An oscillator circuit attached to the filter matrix propagates acoustic vibration, further causing water molecules to de-bond and move through the filter. This use of acoustics also eliminates dependence on gravity (and thus filter orientation) to move water through the device. When water exiting the system diminishes to a pre-determined set point, a cleaning cycle is triggered to clear the sediment from the inlet of the filter, reestablishing the standard system flow rate. Unlike other filtration systems, flushing of the filter system is not required. The combination of acoustics and small-diameter carbon nanotubes in this innovation make it an effective and efficient means of producing contaminant-free, clean water.

The CSV replaces a standard spacecraft Fill and Drain Valve to facilitate cooperative servicing. The CSV offers various advantages over standard service valves: a robotic interface, three individually actuated seals, a self-contained anti-back drive system, and built-in thermal isolation. When mounted to a spacecraft as designed, the CSV transfers all operational and induced robotic loads to the mounting structure. An anti-back drive mechanism prevents the CSV seal mechanism from inadvertent actuation. Alignment marks, thermal isolation, and a mechanical coupling capable of reacting operational and robotic loads optimize the CSV for tele-robotic operations. Unique keying of the mating interface prevents mixing of media where more than one configuration of the CSV is used. Color-coding and labels are also used to prevent operator error. The CSV has four configurations for different working fluids, all with essentially unchanged geometry and mechanics.

The Multi-Link Spherical Joint developed at NASA Johnson Space Center provides a substantial improvement over typical joints in which only two linearly actuated links move independently from one another. It was determined that the rotation point of a trussed link needed to be collocated at a shared point in space for maximum articulation. If not allowed separate rotation, the line of action through a universal joint and hinge acts effectively as another linkage. This leads to a much more complex and uncontrollable structure, especially when considering multiple dimensions. Comprising the Multi-Link Spherical Joint, a spherical shell encases the cupped ends of each six possible attachments and allows each of those attachments to be independently controlled and rotated without inhibiting the motion of the others. To do this, each link is precisely limited to 15 degrees of rotation off the link centerline, thus allowing a total of 30 degrees of rotation for each link. The shell-and-cup structure can handle the loads of linear actuators that may be used to control and vary the geometry of a truss system utilizing the new joint technology. The calculated operating load that the truss system must handle can be used to scale the size of the joint, further allowing customization of any potential truss system. Additionally, the incorporated linear actuators can be controlled and powered by wiring routed through the joint without putting undo stress on the wires during operation. Accordingly, this innovative joint technology enables more efficient deployment and precise operation of articulating structures. The Multi-Link Spherical Joint is at technology readiness level (TRL) 4 (component and/or breadboard validation in laboratory environment) and is available for patent licensing. Please note that NASA does not manufacture products itself for commercial sale.

Space and ground launch support related hardware often operate under extreme pressure, temperature, and corrosive conditions. When dealing with this type of equipment, it is frequently necessary to run wiring, tubes, or fibers through a barrier separating one process from another with one or both operating in extreme environments. Feedthroughs used to route the wiring, tubes, or fibers through these barriers must meet stringent sealing and leak tightness requirements. This affordable NASA feedthrough meets or exceeds all sealing and leak requirements utilizing easy-to-assemble commercial-off-the-shelf hardware with no special tooling. The feedthrough is a fully reconfigurable design; however, it can also be produced as a permanent device. Thermal cycling and helium mass spectrometer leak testing under extreme conditions of full cryogenic temperatures and high vacuum have proven the sealing capability of this feedthrough with or without potting (epoxy fill) on the ends. Packing material disks used in the construction of the device can be replaced as needed for rebuilding a given feedthrough for another job or a different set of feeds if potting is not used for the original feedthrough build. (Potting on one or both sides of the sleeve provides double or triple leak sealing protection). Variable Compression Ratio (VCR) connectors were adapted for the pressure seal on the feedthrough; however, any commercial connector can be similarly adapted. The design can easily be scaled up to larger (2" diameter) and even very large (12" or more) sizes.