Portable Science Enclosure Features Unique Innovations

The Compact Science Experiment Module (CSEM) provides a suitable experiment platform consisting of an enclosure that contains all the required components to perform science experiments that can house either living biological samples or other samples on both the ground and on the International Space Station (ISS). The invention provides required instrumentation for video capture and data storage, environmental monitoring, inclusive of sensing temperature in degree Celsius, relative humidity as a percentage, carbon dioxide in parts per million and oxygen in percentage format. Data can be stored within the module and retrieved after the experiment or can be transmitted to the ground as for example from the ISS, by connecting to the ISS telemetry system. The Compact Life Science Experiment Module has been fully developed at NASA Ames Research Center and tested on the ISS. In general, fruit fly studies can provide information about the effects of spaceflight at the biochemical, cellular and organismal levels. Using fruit fly spaceflight hardware, researchers are able to investigate the role of spaceflight on development, growth, reproduction, aging, neurobehavioral responses, immunity, heart function, etc. The fruit fly genome matches the human disease genome by almost 77%, and flies have, therefore, been a useful tool for scientists to understand the genetics, and molecular biology of more complex biological systems like humans. The Compact Science Experiment Module is extremely adaptable to other model specimens and samples as well, and has also flown plant experiments on the ISS. The software can be tailored to accommodate different experiment scenarios by adjusting video imaging times, LED light cycles, data storage and telemetry etc.

NASA's Liquid Sorbent Carbon Dioxide Removal System was designed as an alternative to the current CO2 removal technology used on the International Space Station (ISS), which uses solid zeolite media that is prone to dusting, has a low absorption capacity, and requires high regeneration temperatures and frequent maintenance. Motivated by CO2 removal systems on submarines, NASA innovators began investigating the use of liquid sorbents. Liquid sorbents have a capacity four times greater than solid zeolites, require low regeneration temperature, and need fewer unreliable moving mechanical parts than solid based systems. While submarine CO2 scrubbers spray an adsorbing chemical directly into the air stream and allow the liquid to settle, NASA's new system uses a capillary driven 3D printed microchannel direct air/liquid contactor in a closed loop system. The Liquid Sorbent Carbon Dioxide Removal System is robust and reliable, while being low in weight, volume, and power requirements. The system is capable of reaching equilibrium when the liquid sorbent surface is being regenerated at a rate equal to the rate of absorption into the liquid.

Bacterial contamination of water systems used in microgravity is a major issue for NASA because biofilms can clog or interfere with water system functions and bacterial ingestion can be harmful to astronaut health. To address this problem, NASA innovators developed a microwave based technology to purify contaminated water by eradicating and eliminating bacteria that grows in systems that generate potable water, in equipment utilizing cooling loops and heat exchangers, and removing bacterial contamination that is present on a variety of surfaces. This decontamination system is chemical free and requires minimal to no consumables. Initial testing identified a specific microwave frequency band and exposure times for killing bacteria (Burkholderia cepacia) and biofilm. Test results show that exposing static water to microwave energy for 90 seconds can effectively kill waterborne bacteria and biofilm within a water filtration system. Additional testing, using a circulating water test bed, demonstrated that microwave energy at the selected frequency can effectively eradicate waterborne bacteria within 30 seconds. This technology could be further developed into a portable, lightweight system for use in remote locations as well as commercial space applications. The microwave decontamination system could also be added to existing water systems to extend the life of the system.

This approach allows water recycling, air treatment, thermal control, and solids residuals treatment and recycle to be removed from the usable habitat volume and placed in the walls of a radiation-shielding water wall. It also provides a mechanism to recover and reuse water treatment (solids) residuals to strengthen the habitat shell. Water-wall treatment elements are a much-enlarged version of the commercially available X-Pack hydration bag. Some water bags have pervaporation membranes facing inward that provide the capability to remove H0, C0, and trace organics from the atmosphere. Ideally the water wall is composed of a series of membrane bags packed as dry elements integrated into an inflatable habitat structure wall. After launch and deployment, it is filled with water and maintained as both a freshwater supply and radiation shield. As the initial water supply is consumed, the depleted treatment bags are filled with waste water and take on a dual role of active forward osmosis (FO) water treatment and water-wall radiation shielding.

To stain a specimen slide, one or more liquid reagents are injected via the dispenser into the slide staining device via a syringe port. The volume of a given reagent is determined by adjustable settings on the dispenser, so that when connected to the staining device, initiates a thin film over the slide. The dispensing device uses only a fraction of the reagents typically used in non-sealed environments. Medical grade polyvinyl alcohol sponges have been incorporated into the dispenser to provide additional fluid containment and retention during the staining procedure. Furthermore, the dispenser can recall excess reagent, minimizing reagent use until refill. The slide staining device is composed of an upper and lower section held together and aligned by use of Nd magnets. With the device open, a specimen slide is positioned upon a silicone gasket that sits within a recess in the lower section. When the device is closed, the silicone gasket in the upper section applies a seal to the slide forming a cavity that allows the slide to be exposed to reagents injected from the connected dispenser creating a stain through the use of capillary forces. Although originally designed for use in microgravity, the slide staining system also works in gravity environments. Numerous applications may exist for this technology, particularly in hematology and cellular biology. Other applications could be considered for academic research, veterinary field use, military, disaster stricken and remote environments or where fine control of fluid delivery, removal, and management is desired. The slide staining system is at technology readiness level (TRL) 8 (actual system completed and "flight qualified" through test and demonstration), and are now available to license. Please note that NASA does not manufacture products itself for commercial sale.